Noninvasive Assessment of Fractional Flow Reserve Using Mathematical Modeling of Coronary Flow

Comprehensive assessment of coronary fractional flow reserve

Fractional flow reserve (FFR) is considered nowadays as the gold standard for invasive assessment of physiologic stenosis significance and an indispensable tool for decision-making in coronary revascularization. Robust studies have shown that FFR is more effective in accurately identifying which lesions should be stented, and revascularization guided by FFR improves the outcome of coronary arte...

Coronary Computed Tomography Angiography With Selective Noninvasive Fractional Flow Reserve

Coronary Computed Tomography Angiography With Selective Noninvasive Fractional Flow Reserve

Based on review of available data, the Company may consider the use of noninvasive fractional flow reserve (FFR) following a positive coronary computed tomography angiography (CCTA) to guide decisions about the use of invasive coronary angiography (ICA) in patients with stable chest pain at intermediate risk of coronary artery disease (CAD i.e., suspected or presumed stable ischemic heart disea...

Coronary Computed Tomography Angiography with Selective Noninvasive Fractional Flow Reserve

Fractional flow reserve using coronary computed tomography angiography requires at least 64slice coronary computed tomography angiography and cannot be calculated when images lack sufficient quality (HeartFlow, 2013) (11% to 13% in recent studies; Koo et al, 2011; Min et al, 2012; Nakazato et al, 2013; Nørgaard et al, 2014), e.g., in obese individuals (e.g., body mass index, >35 kg/m2). The pre...

Coronary Computed Tomography Angiography With Selective Noninvasive Fractional Flow Reserve